MAGEA9 Antikörper (AA 171-198)

Produktnummer ABIN390111

Dieses Anti-MAGEA9-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von MAGEA9 in WB und IHC (p). Geeignet für Human. Dieses Primary Antibody wurde in 3+ Publikationen zitiert.

Kurzübersicht für MAGEA9 Antikörper (AA 171-198) (ABIN390111)

Target: MAGEA9 (Melanoma Antigen Family A, 9 (MAGEA9))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAGEA9 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB2099

Produktdetails anti-MAGEA9 Antikörper

Bindungsspezifität: AA 171-198

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This MAGEA9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 171-198 amino acids from the Central region of human MAGEA9.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-MAGEA9 Antikörper (ABIN390111)

Zhang, Zhai, Wang, Feng, Zhu, Xu, Mao, Huang: "High expression of MAGE-A9 in tumor and stromal cells of non-small cell lung cancer was correlated with patient poor survival." in: International journal of clinical and experimental pathology, Vol. 8, Issue 1, pp. 541-50, (2015) (PubMed).

Zhan, Zhang, Zhang, Ma, Wu, Gu, Li, Yang: "Prognostic value of MAGE-A9 expression in patients with colorectal cancer." in: Clinics and research in hepatology and gastroenterology, (2015) (PubMed).

Han, Jiang, Wu, Zhang, Lu: "Expression and prognostic value of MAGE-A9 in laryngeal squamous cell carcinoma." in: International journal of clinical and experimental pathology, Vol. 7, Issue 10, pp. 6734-42, (2014) (PubMed).

Details zu MAGEA9

Target: MAGEA9 (Melanoma Antigen Family A, 9 (MAGEA9))

Andere Bezeichnung: MAGEA9

Hintergrund: MAGEA9 is a member of the MAGEA gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 80 % sequence identity between each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are expressed at a high level in a number of tumors of various histologic types, and are silent in normal tissues with the exception of testis and placenta. The MAGEA genes are clustered on chromosome Xq28. They may be implicated in some hereditary disorders, such as dyskeratosis congenita.

Gen-ID: 4108

NCBI Accession: NP_001074259, NP_005356

UniProt: P43362