IRS2 Antikörper (pTyr978)

Produktnummer ABIN389979

Der Kaninchen Polyklonal anti-IRS2 Antikörper (Klon RB15626) (ABIN389979) detektiert spezifisch IRS2 in DB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für IRS2 Antikörper (pTyr978) (ABIN389979)

Target: IRS2 (Insulin Receptor Substrate 2 (IRS2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IRS2 Antikörper ist unkonjugiert

Applikation: Dot Blot (DB)

Klon: RB15626

Produktdetails anti-IRS2 Antikörper

Bindungsspezifität: pTyr978

Homologie: M

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This IRS2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y978 of human IRS2.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: DB: 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu IRS2

Target: IRS2 (Insulin Receptor Substrate 2 (IRS2))

Andere Bezeichnung: IRS2

Hintergrund: Insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. This protein is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment.

Gen-ID: 8660

NCBI Accession: NP_003740

UniProt: Q9Y4H2

Pathways: Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Positive Regulation of Peptide Hormone Secretion, Response to Growth Hormone Stimulus, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process