ANTXR1 Antikörper (pTyr382)

Produktnummer ABIN389930

Der Kaninchen Polyklonal Anti-ANTXR1-Antikörper wurde für DB validiert. Er ist geeignet, ANTXR1 in Proben von Human zu detektieren.

Kurzübersicht für ANTXR1 Antikörper (pTyr382) (ABIN389930)

Target: ANTXR1 (anthrax Toxin Receptor 1 (ANTXR1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ANTXR1 Antikörper ist unkonjugiert

Applikation: Dot Blot (DB)

Klon: RB15324

Produktdetails anti-ANTXR1 Antikörper

Bindungsspezifität: pTyr382

Homologie: M, Rat

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ANTXR1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y382 of human ANTXR1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: DB: 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu ANTXR1

Target: ANTXR1 (anthrax Toxin Receptor 1 (ANTXR1))

Andere Bezeichnung: ANTXR1

Hintergrund: ANTXR1 is a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. This protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes.

Molekulargewicht: 62789

Gen-ID: 84168

NCBI Accession: NP_060623, NP_115584, NP_444262

UniProt: Q9H6X2