HIST1H3B3 (pSer10) Antikörper

Produktnummer ABIN389570

Der Kaninchen Polyklonal anti-HIST1H3B3 Antikörper wird verwendet zum Nachweis von HIST1H3B3 in Proben von Human. Er wurde validiert für DB, WB, IF und IHC (p).

Kurzübersicht für HIST1H3B3 (pSer10) Antikörper (ABIN389570)

Target: HIST1H3B3

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Dot Blot (DB), Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB2673-RB2674

Produktdetails

Bindungsspezifität: pSer10

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This HIST1H3B3 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S10 of human HIST1H3B3.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: IF: 1:25. WB: 1:500. WB: 1:500. IHC-P-Leica: 1:100. IHC-P-Leica: 1:100. DB: 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze-thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.

Haltbarkeit: 6 months

Antigendetails

Target: HIST1H3B3

Hintergrund: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails, instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.

Molekulargewicht: 15404

Gen-ID: 8968

NCBI Accession: NP_003520, NP_003521, NP_003522, NP_003523, NP_003524, NP_003525, NP_003526, NP_003527, NP_003528, NP_066298

UniProt: P68431