Der Kaninchen Polyklonal Anti-APRT-Antikörper wurde für WB, IF, FACS und IHC (p) validiert. Er ist geeignet, APRT in Proben von Human zu detektieren. Es ist 1 Publikation verfügbar.
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This APRT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 12-40 amino acids from the N-terminal region of human APRT.
A conserved feature of APRT is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis.