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FOXP3 Antikörper (C-Term)

Dieses Anti-FOXP3-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von FOXP3 in WB, FACS und IHC (p). Geeignet für Human und Maus. Dieses Primary Antibody wurde in 4+ Publikationen zitiert.
Produktnummer ABIN389295

Kurzübersicht für FOXP3 Antikörper (C-Term) (ABIN389295)

Target

Alle FOXP3 Antikörper anzeigen
FOXP3 (Forkhead Box P3 (FOXP3))

Reaktivität

  • 171
  • 144
  • 66
  • 28
  • 7
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Maus

Wirt

  • 120
  • 82
  • 20
  • 2
Kaninchen

Klonalität

  • 118
  • 106
Polyklonal

Konjugat

  • 113
  • 15
  • 12
  • 10
  • 8
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Dieser FOXP3 Antikörper ist unkonjugiert

Applikation

  • 138
  • 93
  • 66
  • 53
  • 42
  • 37
  • 30
  • 29
  • 27
  • 17
  • 10
  • 8
  • 7
  • 6
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon

RB17111
  • Bindungsspezifität

    • 16
    • 15
    • 11
    • 11
    • 7
    • 6
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 283-311, C-Term

    Homologie

    Pr

    Aufreinigung

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    Immunogen

    This FOXP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 283-311 amino acids from the C-terminal region of human FOXP3.

    Isotyp

    Ig Fraction
  • Applikationshinweise

    WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    Haltbarkeit

    6 months
  • Sun, Feng, Wang, Qu, Gai: "Expression of Foxp3 and its prognostic significance in colorectal cancer." in: International journal of immunopathology and pharmacology, Vol. 30, Issue 2, pp. 201-206, (2018) (PubMed).

    Zha, Huang, Lin, Liu, Hou, Wu: "Distribution of lymphocyte subpopulations in thyroid glands of human autoimmune thyroid disease." in: Journal of clinical laboratory analysis, Vol. 28, Issue 3, pp. 249-54, (2015) (PubMed).

    Liu, Lu, Feng, Ding, Gao, Ge, Wang: "Up-regulated expression of indoleamine 2,3-dioxygenase 1 in non-Hodgkin lymphoma correlates with increased regulatory T-cell infiltration." in: Leukemia & lymphoma, Vol. 55, Issue 2, pp. 405-14, (2014) (PubMed).

    Dou, Feng, Liu, Wang: "Cyclic adenosine monophosphate involvement in low-dose cyclophosphamide-reversed immune evasion in a mouse lymphoma model." in: Cellular & molecular immunology, Vol. 9, Issue 6, pp. 482-8, (2013) (PubMed).

  • Target

    FOXP3 (Forkhead Box P3 (FOXP3))

    Andere Bezeichnung

    FOXP3

    Hintergrund

    FOXP3 is a member of the forkhead/winged-helix family of transcriptional regulators. Defects in FOXP3 gene are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome.

    Molekulargewicht

    47244

    Gen-ID

    50943

    NCBI Accession

    NP_001107849, NP_054728

    UniProt

    Q9BZS1

    Pathways

    Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
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