Vimentin Antikörper (C-Term)
Kurzübersicht für Vimentin Antikörper (C-Term) (ABIN389212)
Target
Alle Vimentin (VIM) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 430-457, C-Term
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Homologie
- X, B, C, Ha, Pr, M, Pig, Rat
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Aufreinigung
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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Immunogen
- This Vimentin antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 430-457 amino acids from the C-terminal region of human Vimentin.
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Isotyp
- Ig Fraction
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Applikationshinweise
- IF: 1:100. WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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Haltbarkeit
- 6 months
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Pituitary tumor transforming gene PTTG2 induces psoriasis by regulating vimentin and E-cadherin expression." in: International journal of clinical and experimental pathology, Vol. 8, Issue 9, pp. 10887-93, (2016) (PubMed).
: "Down-regulation of TCF21 by hypermethylation induces cell proliferation, migration and invasion in colorectal cancer." in: Biochemical and biophysical research communications, (2015) (PubMed).
: "
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Pituitary tumor transforming gene PTTG2 induces psoriasis by regulating vimentin and E-cadherin expression." in: International journal of clinical and experimental pathology, Vol. 8, Issue 9, pp. 10887-93, (2016) (PubMed).
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- Vimentin (VIM)
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Andere Bezeichnung
- Vimentin
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Hintergrund
- Along with the microfilaments (actins) and microtubules (tubulins), the intermediate filaments represent a third class of well-characterized cytoskeletal elements. The subunits display a tissue-specific pattern of expression. Desmin is the subunit specific for muscle and vimentin the subunit specific for mesenchymal tissue.
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Molekulargewicht
- 53652
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Gen-ID
- 7431
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NCBI Accession
- NP_003371
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UniProt
- P08670
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Pathways
- Caspase Kaskade in der Apoptose
Target
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