ACSL6 Antikörper (AA 240-270)

Produktnummer ABIN389115

Dieses Anti-ACSL6-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von ACSL6 in WB und IHC (p). Geeignet für Human und Maus.

Kurzübersicht für ACSL6 Antikörper (AA 240-270) (ABIN389115)

Target: ACSL6 (Acyl-CoA Synthetase Long-Chain Family Member 6 (ACSL6))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ACSL6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB4703

Produktdetails anti-ACSL6 Antikörper

Bindungsspezifität: AA 240-270

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This FACL6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 240-270 amino acids from the Central region of human FACL6.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:50~100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu ACSL6

Target: ACSL6 (Acyl-CoA Synthetase Long-Chain Family Member 6 (ACSL6))

Andere Bezeichnung: FACL6

Hintergrund: FACL6 is involved in activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. It plays an important role in fatty acid metabolism in brain and the acyl-CoAs produced may be utilized exclusively for the synthesis of the brain lipid. FACL6 is expressed predominantly in erythrocyte precursors, in particular in reticulocytes, fetal blood cells derieved from fetal liver, haemopoietic stem cells from cord blood, bone marrow, and brain. Expression is low at earlier stages of erythroid development but is very high in reticulocytes. This protein is involved in myelodysplastic syndrome (MDS) with basophilia, acute myelogenous leukemia (AML) with eosinophilia, and acute eosinophilic leukemia (AEL). It is characterized by a chromosomal translocation t(5,12)(q31,p13) that involves ETV6 and ACSL6.

Molekulargewicht: 77752

Gen-ID: 23305

NCBI Accession: NP_001009185, NP_001192176, NP_001192177, NP_001192179, NP_001192180, NP_056071

UniProt: Q9UKU0