ACOX1 Antikörper (C-Term)

Produktnummer ABIN389100

Dieses Anti-ACOX1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von ACOX1 in WB. Geeignet für Human. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für ACOX1 Antikörper (C-Term) (ABIN389100)

Target: ACOX1 (Acyl-CoA Oxidase 1, Palmitoyl (ACOX1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ACOX1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB04651-04652

Produktdetails anti-ACOX1 Antikörper

Bindungsspezifität: AA 629-659, C-Term

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This ACOX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 629-659 amino acids from the C-terminal region of human ACOX1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-ACOX1 Antikörper (ABIN389100)

Gyamfi, Wan: "Mechanisms of resistance of hepatocyte retinoid X receptor alpha-null mice to WY-14,643-induced hepatocyte proliferation and cholestasis." in: The Journal of biological chemistry, Vol. 284, Issue 14, pp. 9321-30, (2009) (PubMed).

Details zu ACOX1

Target: ACOX1 (Acyl-CoA Oxidase 1, Palmitoyl (ACOX1))

Andere Bezeichnung: ACOX1

Hintergrund: ACOX1 is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. It donates electrons directly to molecular oxygen, thereby producing hydrogen peroxide. Defects in this gene result in pseudoneonatal adrenoleukodystrophy, a disease that is characterized by accumulation of very long chain fatty acids.

Molekulargewicht: 74424

Gen-ID: 51

NCBI Accession: NP_001171968, NP_004026, NP_009223

UniProt: Q15067

Pathways: Regulation of Lipid Metabolism by PPARalpha, Monocarboxylic Acid Catabolic Process