Zitiert in 1 Publikation.
Der Kaninchen Polyklonal anti-ACOX1 Antikörper (Klon RB04651-04652) (ABIN389100) detektiert spezifisch ACOX1 in WB.
Dieser Antikörper reagiert spezifisch mit Proben aus Human.
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen
This ACOX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 629-659 amino acids from the C-terminal region of human ACOX1.
ACOX1
Reaktivität: Human
WB, IF
Wirt: Maus
Polyclonal
unconjugated
Applikationshinweise
WB: 1:1000. WB: 1:1000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Haltbarkeit
6 months
Gyamfi, Wan: "Mechanisms of resistance of hepatocyte retinoid X receptor alpha-null mice to WY-14,643-induced hepatocyte proliferation and cholestasis." in: The Journal of biological chemistry, Vol. 284, Issue 14, pp. 9321-30, (2009) (PubMed).
Target
ACOX1
(Acyl-CoA Oxidase 1, Palmitoyl (ACOX1))
Andere Bezeichnung
ACOX1
Hintergrund
ACOX1 is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. It donates electrons directly to molecular oxygen, thereby producing hydrogen peroxide. Defects in this gene result in pseudoneonatal adrenoleukodystrophy, a disease that is characterized by accumulation of very long chain fatty acids.