Es gibt 1 Publikation für dieses Produkt. Der Kaninchen Polyklonal anti-ACOX1 Antikörper wird verwendet zum Nachweis von ACOX1 in Proben von Human und Maus. Er wurde validiert für IHC (p).
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen
This ACOX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 7-37 amino acids from the N-terminal region of human ACOX1.
ACOX1
Reaktivität: Human
WB, IF
Wirt: Maus
Polyclonal
unconjugated
Applikationshinweise
IHC-P: 1:10~50
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Haltbarkeit
6 months
Bagattin, Hugendubler, Mueller: "Transcriptional coactivator PGC-1alpha promotes peroxisomal remodeling and biogenesis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 47, pp. 20376-81, (2010) (PubMed).
Target
ACOX1
(Acyl-CoA Oxidase 1, Palmitoyl (ACOX1))
Andere Bezeichnung
ACOX1
Hintergrund
ACOX1 is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. It donates electrons directly to molecular oxygen, thereby producing hydrogen peroxide. Defects in this gene result in pseudoneonatal adrenoleukodystrophy, a disease that is characterized by accumulation of very long chain fatty acids.