CBX8 Antikörper (C-Term)
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- Target Alle CBX8 Antikörper anzeigen
- CBX8 (Chromobox Homolog 8 (CBX8))
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Bindungsspezifität
- AA 306-337, C-Term
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CBX8 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This CBX8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 306-337 amino acids from the C-terminal region of human CBX8.
- Klon
- RB2937
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product CBX8 Primärantikörper
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- Applikationshinweise
- WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Haltbarkeit
- 6 months
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- Target
- CBX8 (Chromobox Homolog 8 (CBX8))
- Andere Bezeichnung
- CBX8 (CBX8 Produkte)
- Hintergrund
- Chromobox homolog 8 (CBX8 or Pc3) is a member of Drosophila Polycomb group gene family. The polycomb group (PcG) genes are essential for maintenance of appropriate expression patterns of developmental master regulators and thus are essential for proper development. Changes in expression of PcG proteins have been associated with cancer. CBX8 is involved in maintaining the transcriptionally repressive state of genes. It modifies chromatin, rendering it heritably changed in its expressibility. Structurally, CBX4 contains 1 chromo domain, which is 40 to 50 amino acids long.
- Molekulargewicht
- 43396
- Gen-ID
- 57332
- NCBI Accession
- NP_065700
- UniProt
- Q9HC52
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