PIGK Antikörper (N-Term)

Produktnummer ABIN389064

Dieses Anti-PIGK-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von PIGK in WB und IHC (p). Geeignet für Human. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für PIGK Antikörper (N-Term) (ABIN389064)

Target: PIGK (GPI8) (GPI-anchor transamidase (GPI8))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PIGK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB4714

Produktdetails anti-PIGK Antikörper

Bindungsspezifität: AA 37-68, N-Term

Homologie: B, M, Pig

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This GPI8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-68 amino acids from the N-terminal region of human GPI8.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:50~100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-PIGK Antikörper (ABIN389064)

Nagpal, Dasgupta, Jadallah, Chae, Ratovitski, Toubaji, Netto, Eagle, Nissan, Sidransky, Trink: "Profiling the expression pattern of GPI transamidase complex subunits in human cancer." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 21, Issue 8, pp. 979-91, (2008) (PubMed).

Details zu PIGK

Target: PIGK (GPI8) (GPI-anchor transamidase (GPI8))

Andere Bezeichnung: GPI8

Hintergrund: GPI8 is a member of the cysteine protease family C13 that is involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This protein is a member of the multisubunit enzyme, GPI transamidase and is thought to be its enzymatic component. GPI transamidase mediates GPI anchoring in the endoplasmic reticulum, by catalyzing the transfer of fully assembled GPI units to proteins.

Molekulargewicht: 45252

Gen-ID: 10026

NCBI Accession: NP_005473

UniProt: Q92643