Epsin 2 Antikörper (N-Term)
Kurzübersicht für Epsin 2 Antikörper (N-Term) (ABIN388977)
Target
Alle Epsin 2 (EPN2) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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    - 
                                            Bindungsspezifität
- AA 6-36, N-Term
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                                            Homologie
- Rat
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                                            Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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                                            Immunogen
- This Epsin2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 6-36 amino acids from the N-terminal region of human Epsin2.
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                                            Isotyp
- Ig Fraction
 
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    - 
                                            Applikationshinweise
- WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100
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                                            Beschränkungen
- Nur für Forschungszwecke einsetzbar
 
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    - 
                                            Format
- Liquid
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                                            Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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                                            Konservierungsmittel
- Sodium azide
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                                            Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            Lagerung
- 4 °C,-20 °C
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                                            Informationen zur Lagerung
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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                                            Haltbarkeit
- 6 months
 
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    - 
                                            : "Endocytic recycling protein EHD1 regulates primary cilia morphogenesis and SHH signaling during neural tube development."    in: Scientific reports, Vol. 6, pp. 20727, (2016)         (PubMed).        
 
 
- 
                                            : "Endocytic recycling protein EHD1 regulates primary cilia morphogenesis and SHH signaling during neural tube development."    in: Scientific reports, Vol. 6, pp. 20727, (2016)         (PubMed).        
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    - Epsin 2 (EPN2)
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                                            Andere Bezeichnung
- Epsin2
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                                            Hintergrund
- Epsin2 plays a role in the formation of clathrin-coated invaginations and endocytosis. It binds to EPS15 (via the NPF repeat domain), as well as to AP-2 and clathrin (via the DPW repeat domain). The protein resides in the cytoplasm, in punctate structures throughout the cell, associated with clathrin-coated vesicles, and is particularly concentrated in the region of the Golgi complex. Highest expression is found in brain, with lower levels detected in lung and liver.
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                                            Molekulargewicht
- 68482
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                                            Gen-ID
- 22905
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                                            NCBI Accession
- NP_001096134, NP_055779, NP_683723
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                                            UniProt
- O95208
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                                            Pathways
- EGFR Downregulation
 Target
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