Epsin 2 Antikörper (N-Term)

Produktnummer ABIN388977

Dieses Anti-Epsin 2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Epsin 2 in WB und IHC (p). Geeignet für Human und Maus. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für Epsin 2 Antikörper (N-Term) (ABIN388977)

Target: Epsin 2 (EPN2)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Epsin 2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB4610

Produktdetails anti-Epsin 2 Antikörper

Bindungsspezifität: AA 6-36, N-Term

Homologie: Rat

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This Epsin2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 6-36 amino acids from the N-terminal region of human Epsin2.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-Epsin 2 Antikörper (ABIN388977)

Bhattacharyya, Rainey, Arya, Mohapatra, Mushtaq, Dutta, George, Storck, McComb, Muirhead, Todd, Gould, Datta, Gelineau-van Waes, Band, Band: "Endocytic recycling protein EHD1 regulates primary cilia morphogenesis and SHH signaling during neural tube development." in: Scientific reports, Vol. 6, pp. 20727, (2016) (PubMed).

Details zu Epsin 2

Target: Epsin 2 (EPN2)

Andere Bezeichnung: Epsin2

Hintergrund: Epsin2 plays a role in the formation of clathrin-coated invaginations and endocytosis. It binds to EPS15 (via the NPF repeat domain), as well as to AP-2 and clathrin (via the DPW repeat domain). The protein resides in the cytoplasm, in punctate structures throughout the cell, associated with clathrin-coated vesicles, and is particularly concentrated in the region of the Golgi complex. Highest expression is found in brain, with lower levels detected in lung and liver.

Molekulargewicht: 68482

Gen-ID: 22905

NCBI Accession: NP_001096134, NP_055779, NP_683723

UniProt: O95208

Pathways: EGFR Downregulation