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USP13 Antikörper (N-Term)

USP13 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB4301 unconjugated
Produktnummer ABIN388900
  • Target Alle USP13 Antikörper anzeigen
    USP13 (Ubiquitin Specific Peptidase 13 (Isopeptidase T-3) (USP13))
    Bindungsspezifität
    • 9
    • 7
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 156-186, N-Term
    Reaktivität
    • 58
    • 32
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Human
    Wirt
    • 57
    • 4
    Kaninchen
    Klonalität
    • 49
    • 12
    Polyklonal
    Konjugat
    • 32
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser USP13 Antikörper ist unkonjugiert
    Applikation
    • 46
    • 28
    • 19
    • 6
    • 6
    • 5
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Homologie
    B
    Aufreinigung
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This USP13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 156-186 amino acids from the N-terminal region of human USP13.
    Klon
    RB4301
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product USP13 Primärantikörper
  • Applikationshinweise
    WB: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Target
    USP13 (Ubiquitin Specific Peptidase 13 (Isopeptidase T-3) (USP13))
    Andere Bezeichnung
    USP13 (USP13 Produkte)
    Synonyme
    ISOT3 antikoerper, IsoT-3 antikoerper, 2700071E21Rik antikoerper, AI848077 antikoerper, usp13 antikoerper, MGC163140 antikoerper, ubiquitin specific peptidase 13 antikoerper, ubiquitin specific peptidase 13 (isopeptidase T-3) antikoerper, ubiquitin carboxyl-terminal hydrolase 13 antikoerper, universal stress protein antikoerper, USP13 antikoerper, Usp13 antikoerper, usp13 antikoerper, MGYG_01656 antikoerper, RR_RS02895 antikoerper
    Hintergrund
    Modification of target proteins by ubiquitin participates in a wide array of biological functions. Proteins destined for degradation or processing via the 26 S proteasome are coupled to multiple copies of ubiquitin. However, attachment of ubiquitin or ubiquitin-related molecules may also result in changes in subcellular distribution or modification of protein activity. An additional level of ubiquitin regulation, deubiquitination, is catalyzed by proteases called deubiquitinating enzymes, which fall into four distinct families. Ubiquitin C-terminal hydrolases, ubiquitin-specific processing proteases (USPs),1 OTU-domain ubiquitin-aldehyde-binding proteins, and Jab1/Pad1/MPN-domain-containing metallo-enzymes. Among these four families, USPs represent the most widespread and represented deubiquitinating enzymes across evolution. USPs tend to release ubiquitin from a conjugated protein. They display similar catalytic domains containing conserved Cys and His boxes but divergent N-terminal and occasionally C-terminal extensions, which are thought to function in substrate recognition, subcellular localization, and protein-protein interactions.
    Molekulargewicht
    97327
    Gen-ID
    8975
    NCBI Accession
    NP_003931
    UniProt
    Q92995
    Pathways
    SARS-CoV-2 Protein Interaktom
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