RPL23A Antikörper (C-Term)

Produktnummer ABIN388651

Produktdetails anti-RPL23A Antikörper

Target: RPL23A (Ribosomal Protein L23A (RPL23A))

Bindungsspezifität: AA 111-140, C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RPL23A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: B

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This RPL23A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 111-140 amino acids from the C-terminal region of human RPL23A.

Klon: RB9668

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:2000. IHC-P: 1:100. IHC-P: 1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-RPL23A Antikörper (ABIN388651)

Wang, DiMario: "Loss of Drosophila nucleostemin 2 (NS2) blocks nucleolar release of the 60S subunit leading to ribosome stress." in: Chromosoma, Vol. 126, Issue 3, pp. 375-388, (2018) (PubMed).

James, Cindass, Mayer, Terhoeve, Mumphrey, DiMario: "Nucleolar stress in Drosophila melanogaster: RNAi-mediated depletion of Nopp140." in: Nucleus (Austin, Tex.), Vol. 4, Issue 2, pp. 123-33, (2013) (PubMed).

Details zu RPL23A

Target: RPL23A (Ribosomal Protein L23A (RPL23A))

Andere Bezeichnung: RPL23A (RPL23A Produkte)

Hintergrund: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. RPL23A is a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L23P family of ribosomal proteins. It is located in the cytoplasm. The protein may be one of the target molecules involved in mediating growth inhibition by interferon. In yeast, the corresponding protein binds to a specific site on the 26S rRNA. This gene is co-transcribed with the U42A, U42B, U101A, and U101B small nucleolar RNA genes, which are located in its third, first, second, and fourth introns, respectively.

Molekulargewicht: 17695

Gen-ID: 6147

NCBI Accession: NP_000975

UniProt: P62750