UVRAG Antikörper (AA 366-398)
Kurzübersicht für UVRAG Antikörper (AA 366-398) (ABIN388587)
Target
Alle UVRAG Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
-
-
Bindungsspezifität
- AA 366-398
-
Aufreinigung
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
-
Immunogen
- This UVRAG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 366-398 amino acids from the Central region of human UVRAG.
-
Isotyp
- Ig Fraction
-
-
-
-
Applikationshinweise
- WB: 1:1000. IHC-P: 1:10~50
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- 4 °C,-20 °C
-
Informationen zur Lagerung
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
-
Haltbarkeit
- 6 months
-
-
- UVRAG (UV Radiation Resistance Associated Gene (UVRAG))
-
Andere Bezeichnung
- UVRAG
-
Hintergrund
- UVRAG complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1-PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left-right axis malformation and mutations in this gene have been associated with colon cancer.
-
Molekulargewicht
- 78151
-
Gen-ID
- 7405
-
NCBI Accession
- NP_003360
-
UniProt
- Q9P2Y5
Target
-