BMP7 Antikörper (N-Term)

Produktnummer ABIN388457

Der Kaninchen Polyklonal Anti-BMP7-Antikörper wurde für WB, IF und IHC (p) validiert. Er ist geeignet, BMP7 in Proben von Human zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für BMP7 Antikörper (N-Term) (ABIN388457)

Target: BMP7 (Bone Morphogenetic Protein 7 (BMP7))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BMP7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB1863-1864

Produktdetails anti-BMP7 Antikörper

Bindungsspezifität: AA 15-44, N-Term

Homologie: M

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This Bmp7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-44 amino acids from the N-terminal region of human Bmp7.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: IF: 1:50~100. WB: 1:1000. IHC-P: 1:50~100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-BMP7 Antikörper (ABIN388457)

Li, Chen, Shi, Li, Cai, Zhou, Zhong, Yao: "Angiopoietin-like 4 enhances metastasis and inhibits apoptosis via inducing bone morphogenetic protein 7 in colorectal cancer cells." in: Biochemical and biophysical research communications, Vol. 467, Issue 1, pp. 128-34, (2015) (PubMed).

Details zu BMP7

Target: BMP7 (Bone Morphogenetic Protein 7 (BMP7))

Andere Bezeichnung: Bmp7

Hintergrund: The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, BMP7 has a proposed role in early development. In addition, the fact that BMP7 is closely related to BMP5 and BMP6 has lead to speculation of possible bone inductive activity.

Molekulargewicht: 49313

Gen-ID: 655

NCBI Accession: NP_001710

UniProt: P18075

Pathways: Steroid Hormone Mediated Signaling Pathway, Stem Cell Maintenance