HDAC9 Antikörper (C-Term)

Produktnummer ABIN387961

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch HDAC9 in WB und IHC (p). Er zeigt eine Reaktivität gegenüber Human und wurde in 1 Publikation erwähnt.

Kurzübersicht für HDAC9 Antikörper (C-Term) (ABIN387961)

Target: HDAC9 (Histone Deacetylase 9 (HDAC9))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HDAC9 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB2742

Produktdetails anti-HDAC9 Antikörper

Bindungsspezifität: AA 503-533, C-Term

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This HDAC9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 503-533 amino acids from the C-terminal region of human HDAC9.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:50~100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-HDAC9 Antikörper (ABIN387961)

Lenoir, Flosseau, Ma, Blondeau, Mai, Bassel-Duby, Ravassard, Olson, Haumaitre, Scharfmann: "Specific control of pancreatic endocrine ?- and ?-cell mass by class IIa histone deacetylases HDAC4, HDAC5, and HDAC9." in: Diabetes, Vol. 60, Issue 11, pp. 2861-71, (2011) (PubMed).

Details zu HDAC9

Target: HDAC9 (Histone Deacetylase 9 (HDAC9))

Andere Bezeichnung: HDAC9

Hintergrund: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to the Xenopus and mouse MITR genes. The MITR protein lacks the histone deacetylase catalytic domain. It represses MEF2 activity through recruitment of multicomponent corepressor complexes that include CtBP and HDACs. This encoded protein may play a role in hematopoiesis. Multiple alternatively spliced transcripts have been described for this gene but the full-length nature of some of them has not been determined.

Molekulargewicht: 111297

Gen-ID: 9734

NCBI Accession: NP_001191073, NP_001191074, NP_001191075, NP_001191076, NP_001191077, NP_055522, NP_478056, NP_848510, NP_848512

UniProt: Q9UKV0

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development