PRMT2 Antikörper (N-Term)

Produktnummer ABIN387836

Der Kaninchen Polyklonal Anti-PRMT2-Antikörper wurde für WB und IHC (p) validiert. Er ist geeignet, PRMT2 in Proben von Human zu detektieren.

Kurzübersicht für PRMT2 Antikörper (N-Term) (ABIN387836)

Target: PRMT2 (Protein Arginine Methyltransferase 2 (PRMT2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRMT2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB0027

Produktdetails anti-PRMT2 Antikörper

Bindungsspezifität: AA 22-53, N-Term

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This PRMT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 22-53 amino acids from the N-terminal region of human PRMT2.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu PRMT2

Target: PRMT2 (Protein Arginine Methyltransferase 2 (PRMT2))

Andere Bezeichnung: PRMT2

Hintergrund: Arginine methylation is an irreversible post translational modification which has only recently been linked to protein activity. At least three types of PRMT enzymes have been identified in mammalian cells. These enzymes have been shown to have essential regulatory functions by methylation of key proteins in several fundamental areas. These protein include nuclear proteins, IL enhancer binding factor, nuclear factors, cell cycle proteins, signal transduction proteins, apoptosis proteins, and viral proteins. The mammalian PRMT family currently consists of 7 members that share two large domains of homology. Outside of these domains, epitopes were identified and antibodies against all 7 PRMT members have been developed.

Molekulargewicht: 49042

Gen-ID: 3275

NCBI Accession: NP_001229793, NP_001229794, NP_001526, NP_996845

UniProt: P55345

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding