ICAM1 Antikörper

Produktnummer ABIN379975

Dieser Maus Monoklonal Antikörper detektiert spezifisch ICAM1 in IHC und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für ICAM1 Antikörper (ABIN379975)

Target: ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ICAM1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: 4D10

Produktdetails anti-ICAM1 Antikörper

Spezifität: The antigen is CD54, the antibody recognizes an epitope on domain 1 of the molecule as tested on transfectants. Biochemistry: Clone 1304 stains a 95kD single chain integral membrane glycoprotein. The epitope is stable against acetone or paraformaldehyde fixation. ICAM 1 also functions as a rhinovirus receptor. Antigen distribution: Isolated cells: ICAM-1 expression can be induced on endothelial cells by in vitro stimulation with IL-1, TNF-alpha and IFN-gamma. Tissue sections: In inflamed lesions, the antibody reacts with stimulated endothelial cells, epithelial cells and fibroblasts and with haemopoietic cells such as macrophages, dendritic cells in Peyer's patches, lymph nodes and tonsils. Specificity: Human: CD54. Other: not tested.

Aufreinigung: Affinity purified

Immunogen: cultured human endothelial cells

Anwendungsinformationen

Applikationshinweise: Approved: IHC, IHC-P (1:800)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: 0.5 mL distilled water

Konzentration: Lot specific

Buffer: Lyophilized from PBS  pH 7.2, 10 mg/mL BSA, 0.01 % thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 4°C.

Details zu ICAM1

Target: ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))

Andere Bezeichnung: ICAM1 / CD54

Hintergrund: Name/Gene ID: ICAM1
Family: ICAM

Synonyms: ICAM1, BB2, CD54 antigen, CD54, ICAM-1, p3.58

Gen-ID: 3383

UniProt: P05362

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Regulation of Leukocyte Mediated Immunity, Thromboxane A2 Receptor Signaling