ITGA5 Antikörper (Biotin)

Produktnummer ABIN379959

Dieses Anti-ITGA5-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von ITGA5 in IHC und IHC (fro). Geeignet für Human.

Kurzübersicht für ITGA5 Antikörper (Biotin) (ABIN379959)

Target: ITGA5 (Integrin, alpha 5 (ITGA5))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ITGA5 Antikörper ist konjugiert mit Biotin

Applikation: Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon: X-6

Produktdetails anti-ITGA5 Antikörper (Biotin)

Spezifität: The antigen is a 154-180  kDa protein as determined by immunoprecipitation. The epitope has not been further characterized. Antigen distribution: Isolated cells: Granulocytes, monocytes, positive on blood monocyte-derived macrophages days 0-28. Dull staining with 95 % cord blood CD34+ cells, weak reaction on resting neutrophils. Staining increases with maturation of granulocytes. Treatment with fMLP, TNF, GM-CSF and temperature causes positive shift with granulocytes and monocytes. PMA treatment of granulocytes leads to a decrease in the number of positive cells. Positive with cell lines U937, DH39 & MEP, HL-60, NB4, HMC-1. Tissue sections: X-6 is positive on lining cells in different infiltrations and endothelial cells in the synovial membrane of rheumatoid arthritis patients. The staining pattern is similar to CD34 in these patients. Specificity: Human: granulocytes, monocytes, platelets. Other species: not tested.

Aufreinigung: Affinity purified

Immunogen: Human monocytes

Type of Immunogen: Cells

Anwendungsinformationen

Applikationshinweise: Approved: IHC, IHC-Fr (1:100)

Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: 0.5 mL distilled water

Konzentration: Lot specific

Buffer: Lyophilized from PBS  pH 7.2, 10 mg/mL BSA, 0.01 % thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 4°C.

Details zu ITGA5

Target: ITGA5 (Integrin, alpha 5 (ITGA5))

Andere Bezeichnung: ITGA5/Integrin Alpha 5/CD49e

Hintergrund: Name/Gene ID: ITGA5
Family: Integrin

Synonyms: ITGA5, FNRA, Integrin alpha-5, Integrin Alpha 5, Integrin alpha-F, VLA-5, CD49e, CD49e antigen, VLA5A

Gen-ID: 3678

UniProt: P08648

Pathways: Integrin Complex