CD19 Antikörper (APC)
Kurzübersicht für CD19 Antikörper (APC) (ABIN375780)
Target
Alle CD19 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Spezifität
- Mouse CD19, Mr 95 kDa
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Produktmerkmale
- Mouse Anti-Mouse CD19-APC
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Aufreinigung
- Purified
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Immunogen
- CD19+ mouse pre-B cell line 300.19
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Isotyp
- IgA
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Applikationshinweise
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- Applications: FC - Quality tested , IP - Reported in literature , Activ - Reported in literature
- Working Dilutions: Flow Cytometry FITC and BIOT conjugates 1 g/106 cells APC/CY5.5 and APC/CY7 conjugates 0.3 g/106 cells PE, APC, SPRD, and PE/CY5.5 conjugates 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
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Probenmenge
- 1 mL
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 0.1 mg/mL
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Buffer
- 0.1 mg in 1.0 mL of PBS/Sodium azide and a stabilizing agent
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
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Do not freeze!
Protect conjugated products from light.
Each reagent is stable for the period shown on the bottle label if stored as directed. -
Lagerung
- 4 °C
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Informationen zur Lagerung
- Store at 2-8°C
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- CD19 (CD19 Molecule (CD19))
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Andere Bezeichnung
- CD19
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Hintergrund
- CD19 is a monomeric transmembrane glycoprotein expressed at relatively constant levels throughout B cell development from early pro-B/pre-B cells (i.e., B220 + /CD43 + /HSA + ) through fully differentiated B cell stages. Terminally differentiated plasma cells do not express CD19. In humans, the CD19 molecule on the surface of mature B cells associates with CD21 (CR-2) and CD81 (TAPA-1), and this multimolecular complex synergizes with surface immunoglobulin to provide signal transduction and promote cellular activation. All splenic and peritoneal IgM + cells of both B-1 and B-2 lineages are CD19 +, with B-1 cells expressing higher levels of CD19 than B-2 cells in these sites. Recent studies with CD19-deficient mice have suggested that this molecule may not be required for normal generation and maturation of B cells in the bone marrow.
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Pathways
- Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung
Target
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