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CD8 alpha Antikörper

CD8A Reaktivität: Maus FACS Wirt: Ratte Monoclonal 53-6-7 unconjugated
Produktnummer ABIN375493
  • Target Alle CD8 alpha (CD8A) Antikörper anzeigen
    CD8 alpha (CD8A) (CD8a Molecule (CD8A))
    Reaktivität
    • 200
    • 124
    • 51
    • 46
    • 13
    • 7
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Maus
    Wirt
    • 177
    • 124
    • 108
    Ratte
    Klonalität
    • 307
    • 97
    • 2
    Monoklonal
    Konjugat
    • 134
    • 44
    • 30
    • 28
    • 28
    • 9
    • 9
    • 8
    • 8
    • 8
    • 8
    • 7
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD8 alpha Antikörper ist unkonjugiert
    Applikation
    • 318
    • 119
    • 91
    • 69
    • 64
    • 52
    • 34
    • 21
    • 15
    • 14
    • 14
    • 12
    • 11
    • 9
    • 7
    • 7
    • 6
    • 6
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Spezifität
    Mouse CD8α, Mr 32-34 kDa
    Produktmerkmale
    Rat Anti-Mouse CD8a-LE/AF
    Aufreinigung
    Purified
    Endotoxin-Niveau
    Low endotoxin
    Immunogen
    Spleen cells or thymocyte membranes
    Klon
    53-6-7
    Isotyp
    IgG2a
    Top Product
    Discover our top product CD8A Primärantikörper
  • Applikationshinweise
    • Applications: FC - Quality tested , IHC-FS - Reported in literature , ICC - Reported in literature , IP - Reported in literature , Depletion - Reported in literature , Block - Reported in literature
    • Working Dilutions: Flow Cytometry Purified (UNLB) antibody 2 g/106 cells FITC and BIOT conjugates 2 g/106 cells AF488 conjugate 1 g/106 cells PE, APC, SPRD, PE/TXRD, CY5, PE/CY5.5, PE/CY7, 0.2 g/106 cells APC/CY5.5, APC/CY7, PACBLU, AF647, and AF700 conjugates For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
    Kommentare

    In vivo and in vitro depletion of CD8a+ cells

    Probenmenge
    1 mL
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.5 mg/mL
    Buffer
    0.5 mg of purified immunoglobulin in 1.0 mL of PBS
    Konservierungsmittel
    Azide free
    Handhabung
    Each reagent is stable for the period shown on the bottle label if stored as directed.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Aliquot and freeze the low endotoxin, azide-free product at -20 °C immediately upon receipt.
  • Target
    CD8 alpha (CD8A) (CD8a Molecule (CD8A))
    Andere Bezeichnung
    CD8a (CD8A Produkte)
    Hintergrund
    In the mouse, CD8 exists in two forms: (i) a CD8 heterodimer composed of an α chain (CD8 α /Lyt-2) and a β chain (CD8 β /Lyt-3), and (ii) a homodimer of two α chains. The heterodimer is found on the surface of essentially all thymocytes and the 'suppressor/cytotoxic' subpopulation of mature T lymphocytes. Subsets of intestinal intraepithelial lymphocytes express CD8 α without CD8 β. It has been suggested that CD8 + β - T cells mature extrathymically, while development of the CD8 α + β + population of T cells is thymus-dependent. CD8 acts as a coreceptor with MHC Class I-restricted T cell receptors in antigen recognition and positive selection of MHC class I-restricted CD8 + T cells
    Pathways
    T-Zell Rezeptor Signalweg
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