GPI Antikörper (pSer185)

Produktnummer ABIN375349

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch GPI in WB, ELISA und IHC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für GPI Antikörper (pSer185) (ABIN375349)

Target: GPI (Glucose-6-Phosphate Isomerase (GPI))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GPI Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-GPI Antikörper

Bindungsspezifität: pSer185

Spezifität: Reacts with human 65 kDa GPI protein with a phosphoserine at position 185

Kreuzreaktivität (Details): Do not cross react with non-phospho GPI protein.

Aufreinigung: Antiserum

Immunogen: Synthetic peptide derived from human GPI containing a phosphoserine at position 185

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
- IHC : 1/200 to 1/1 000 - WB : 1/500 to 1/5 000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Must be reconstituted in distilled water.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Haltbarkeit: 24 months

Details zu GPI

Target: GPI (Glucose-6-Phosphate Isomerase (GPI))

Hintergrund: Besides it's role as a glycolytic enzyme, mammalian GPI can function as a tumor-secreted cytokine and an angiogenic factor (AMF) that stimulates endothelial cell motility. GPI is also a neurotrophic factor (Neuroleukin) for spinal and sensory neurons. Phosphorylation at Ser-185 by CK2 has been shown to decrease enzymatic activity and may contribute to secretion by a non-classical secretory pathway.

UniProt: P06744