Acylglycerol Kinase Antikörper (C-Term)
Kurzübersicht für Acylglycerol Kinase Antikörper (C-Term) (ABIN375166)
Target
Alle Acylglycerol Kinase (AGK) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Spezifität
- This antibody reacts to Acylglycerol kinase.
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Kreuzreaktivität (Details)
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Species reactivity (expected):Mouse.
Species reactivity (tested):Human. -
Aufreinigung
- Affinity chromatography
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Immunogen
- Peptide with sequence CDPRKREQMLTSP, from the C Terminus of the protein sequence
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Applikationshinweise
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Peptide ELISA: 1/16000. Western Blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 0,5 mg/mL
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Buffer
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Acylglycerol Kinase (AGK)
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Andere Bezeichnung
- AGK / MULK
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Hintergrund
- Acylglycerol Kinase is a lipid kinase whose function is to phosphorylate monoacylglycerol to form lysophosphatidic acid (LPA) and diacylglycerol to form phosphatidic acid (PA). It does not phosphorylate sphingosine. Overexpression increases the formation and secretion of LPA, resulting in transactivation of EGFR and of the downstream MAPK signaling pathway, thus leading to increased cell growth. It is overexpressed in prostate cancer, where it may play a role in initiation and progression. Two different isoform are known.Synonyms: Acylglycerol kinase, Multiple substrate lipid kinase
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Gen-ID
- 55750
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NCBI Accession
- NP_060708
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UniProt
- Q53H12
Target
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