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Acylglycerol Kinase Antikörper (C-Term)

Dieses Ziege Polyklonal-Antikörper erkennt spezifisch Acylglycerol Kinase in WB und EIA. Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN375166

Kurzübersicht für Acylglycerol Kinase Antikörper (C-Term) (ABIN375166)

Target

Alle Acylglycerol Kinase (AGK) Antikörper anzeigen
Acylglycerol Kinase (AGK)

Reaktivität

  • 27
  • 9
  • 5
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Human

Wirt

  • 22
  • 5
  • 1
Ziege

Klonalität

  • 25
  • 3
Polyklonal

Konjugat

  • 24
  • 2
  • 1
  • 1
Dieser Acylglycerol Kinase Antikörper ist unkonjugiert

Applikation

  • 24
  • 11
  • 10
  • 5
  • 5
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Enzyme Immunoassay (EIA)
  • Bindungsspezifität

    • 7
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    Spezifität

    This antibody reacts to Acylglycerol kinase.

    Kreuzreaktivität (Details)

    Species reactivity (expected):Mouse.
    Species reactivity (tested):Human.

    Aufreinigung

    Affinity chromatography

    Immunogen

    Peptide with sequence CDPRKREQMLTSP, from the C Terminus of the protein sequence
  • Applikationshinweise

    Peptide ELISA: 1/16000. Western Blot: 1 - 3 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    0,5 mg/mL

    Buffer

    Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C/-20 °C

    Informationen zur Lagerung

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target

    Acylglycerol Kinase (AGK)

    Andere Bezeichnung

    AGK / MULK

    Hintergrund

    Acylglycerol Kinase is a lipid kinase whose function is to phosphorylate monoacylglycerol to form lysophosphatidic acid (LPA) and diacylglycerol to form phosphatidic acid (PA). It does not phosphorylate sphingosine. Overexpression increases the formation and secretion of LPA, resulting in transactivation of EGFR and of the downstream MAPK signaling pathway, thus leading to increased cell growth. It is overexpressed in prostate cancer, where it may play a role in initiation and progression. Two different isoform are known.Synonyms: Acylglycerol kinase, Multiple substrate lipid kinase

    Gen-ID

    55750

    NCBI Accession

    NP_060708

    UniProt

    Q53H12
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