CPT1C Antikörper (Internal Region)

Produktnummer ABIN375150

Der Ziege Polyklonal anti-CPT1C Antikörper (ABIN375150) detektiert spezifisch CPT1C in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Hund und Rind (Kuh).

Kurzübersicht für CPT1C Antikörper (Internal Region) (ABIN375150)

Target: CPT1C (Carnitine Palmitoyltransferase 1C (Brain) (CPT1C))

Reaktivität: Human, Hund, Rind (Kuh)

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser CPT1C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CPT1C Antikörper

Bindungsspezifität: Internal Region

Spezifität: This antibody reacts to CPT1C.

Kreuzreaktivität (Details): Species reactivity (expected):Canine, Bovine.
Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography

Immunogen: Peptide with sequence C-KSSTKTDSHRLGQH, from the internal region of the protein sequence

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: 1/16000. Western Blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu CPT1C

Target: CPT1C (Carnitine Palmitoyltransferase 1C (Brain) (CPT1C))

Andere Bezeichnung: CPT1C / CPT1-B

Hintergrund: The Cpt1 family of proteins are outer mitochondrial membrane proteins that regulate the entry into, and oxidation of fatty acids by, mitochondria. Malonyl-CoA, an intermediate in fatty acid synthesis, has been implicated as a regulatory component of the energy sensing system that feeds into hypothalmic neurons to impart energy homeostasis. Malonyl-CoA levels in the hypothalamus are dynamically regulated by fasting and feeding, altering subsequent feeding behaviour. Cpt1c, the brain-specific carnitine O-palmitoyltransferase 1, is thought to relay information about malonyl-CoA levels in hypothalamic neurons that express orexigenic and anorexigenic neuropeptides that regulate food intake and peripheral energy expenditure. Unlike other Cpt1 proteins, Cpt1c binds Malonyl-CoA but does not catalyse the transfer of the malonyl group from CoA to carnitine.Synonyms: CPT IC, Carnitine O-palmitoyltransferase 1, Carnitine palmitoyltransferase 1C, brain isoform

Gen-ID: 126129, 9606

UniProt: Q8TCG5

Pathways: AMPK Signaling, Monocarboxylic Acid Catabolic Process