IDE Antikörper (Internal Region)

Produktnummer ABIN375106

Dieses Ziege Polyklonal-Antikörper erkennt spezifisch IDE in WB. Er zeigt eine Reaktivität gegenüber Human und Hund.

Kurzübersicht für IDE Antikörper (Internal Region) (ABIN375106)

Target: IDE (Insulin-Degrading Enzyme (IDE))

Reaktivität: Human, Hund

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser IDE Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-IDE Antikörper

Bindungsspezifität: Internal Region

Spezifität: This antibody reacts to Insulysin / Insulinase.

Kreuzreaktivität (Details): Species reactivity (expected):Canine.
Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography

Immunogen: Peptide with sequence C-QQYNFDRDNTE, from the internal region of the protein sequence

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: 1/32000. Western Blot: 0.1 - 0.3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu IDE

Target: IDE (Insulin-Degrading Enzyme (IDE))

Andere Bezeichnung: Insulin-Degrading Enzyme

Hintergrund: Insulin degrading enzyme (IDE) has a preferential affinity for insulin such that the presence of insulin will inhibit IDE mediated degradation of other substrates. IDE degrades a variety of other peptides including atrial natriuretic peptide and amylin. IDE catabolizes A beta and has been implicated as a candidate enzyme responsible for the degradation and clearance of A beta in the brain. IDE has also been shown to degrade the APP intracellular domain (AICD), a product of gamma secretase cleaved APP that may function in nuclear signaling.Synonyms: Abeta-degrading protease, EC=3.4.24.56, IDE, Insulin protease, Insulinase, Insulysin

Gen-ID: 3416, 9606

UniProt: P14735

Pathways: SARS-CoV-2 Protein Interaktom