Lactoferrin Antikörper (Internal Region)

Produktnummer ABIN375038

Produktdetails anti-Lactoferrin Antikörper

Target: Lactoferrin (LTF) (Lactotransferrin (LTF))

Bindungsspezifität: Internal Region

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser Lactoferrin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Sequenz: C-ENYKSQQSSD PDP

Spezifität: This antibody detects Lactotransferrin (Internal).

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Immunoaffinity Chromatography

Immunogen: Peptide with sequence from the internal region of the protein sequence according to NP_002334.2. Genename: LTF

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: 1/32000. Western Blot: 0.05 - 0.2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Referenzen für anti-Lactoferrin Antikörper (ABIN375038)

de la Rosa, Yang, Tewary, Varadhachary, Oppenheim: "Lactoferrin acts as an alarmin to promote the recruitment and activation of APCs and antigen-specific immune responses." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 180, Issue 10, pp. 6868-76, (2008) (PubMed).

Details zu Lactoferrin

Target: Lactoferrin (LTF) (Lactotransferrin (LTF))

Andere Bezeichnung: Lactotransferrin (LTF Produkte)

Synonyme: LTF antikoerper, GIG12 antikoerper, HLF2 antikoerper, LF antikoerper, Lf antikoerper, Csp82 antikoerper, MMS10R antikoerper, Ms10r antikoerper, PLF antikoerper, TFEW antikoerper, conalbumin antikoerper, lactotransferrin antikoerper, transferrin antikoerper, transferrin (ovotransferrin) antikoerper, LTF antikoerper, CpipJ_CPIJ000114 antikoerper, TF antikoerper, Ltf antikoerper

Hintergrund: Lactoferrin is an 80 kDa non-haem, iron-binding globular glycoprotein and member of the transferrin family present in milk and mucosal secretions, and also released from neutrophil granules during inflammation. LTF acts as a major first line defense against microbial infections, partly due to its ability to efficiently bind to and hence remove Fe3+ from the environment, but studies have also shown that LTF possesses bactericidal properties and proteolytic activity, capable of cleaving arginine-rich sequences within microbial proteins. Three isoforms of LTF have been identified: LTF-alpha, LTF-beta and LTF-gamma and receptors for LTF are expressed in the gastrointestinal tract, by macrophages, lymphocytes, neutrophils and platelets and also by some bacteria.Synonyms: EC=3.4.21, LF, LTF, Lactoferrin, Talalactoferrin

Gen-ID: 4057, 9606

UniProt: P02788

Pathways: Transition Metal Ion Homeostasis