GALNS Antikörper (Internal Region)

Produktnummer ABIN374878

Dieses Ziege Polyklonal-Antikörper erkennt spezifisch GALNS in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für GALNS Antikörper (Internal Region) (ABIN374878)

Target: GALNS (Galactosamine (N-Acetyl)-6-Sulfate Sulfatase (GALNS))

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser GALNS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GALNS Antikörper

Bindungsspezifität: Internal Region

Sequenz: C-TTHNLEDHTK LP

Spezifität: This antibody detects GALNS.

Kreuzreaktivität (Details): Species reactivity (tested):Human

Aufreinigung: Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Immunogen: Peptide from the internal region of the protein sequence according to NP_000503.1 Genename: GALNS

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: limit dilution 1: 64000. Western blot: 0.01-0.03 μg/mL. Approx 60 kDa band observed in Human Bone Marrow andPlacenta lysates (calculated MW of 58.0 kDa according to NP_000503.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Details zu GALNS

Target: GALNS (Galactosamine (N-Acetyl)-6-Sulfate Sulfatase (GALNS))

Andere Bezeichnung: GALNS

Hintergrund: GALNS (N-acetylgalactosamine-6-sulfatase) is a lysosomal exohydrolase which catalyzes the hydrolysis of the 6-sulfate groups of the N-acetyl-D-galactosamine 6-sulfate units of chondroitin sulfate and of the D-galactose 6-sulfate units of keratan sulfate. Deficiencies of this enzyme lead to Morquio A syndrome, a lysosomal storage disorder.Synonyms: Chondroitinase, Chondroitinsulfatase, EC=3.1.6.4, GalNAc6S sulfatase, Galactose-6-sulfate sulfatase, N-acetylgalactosamine-6-sulfatase, N-acetylgalactosamine-6-sulfate sulfatase

Gen-ID: 2588

NCBI Accession: NP_000503

UniProt: P34059

Pathways: Glycosaminoglycan Metabolic Process