Glucose-6-Phosphate Dehydrogenase Antikörper (Internal Region)

Produktnummer ABIN374802

Produktdetails anti-Glucose-6-Phosphate Dehydrogenase Antikörper

Target: Glucose-6-Phosphate Dehydrogenase (G6PD)

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte, Hund

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser Glucose-6-Phosphate Dehydrogenase Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: C-KPASTNSDDV RDEK

Spezifität: This antibody detetcs G6PD. It is expected to recognise both reported isoforms (NP_000393.4 and NP_001035810.1).

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Rat, DogSpecies reactivity (tested):Human

Aufreinigung: Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Immunogen: Peptide from the internal region of the protein sequence according to NP_000393.4 , NP_001035810.1 Genename: G6PD

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: antibody detection limit dilution 1: 8000. Western blot: 0.1-0.3 μg/mL. Approx 60 kDa band observed in Human Placenta lysates(calculated MW of 62.0 kDa according to NP_000393.4 and 59.0 kDa according toNP_001035810.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.

Details zu Glucose-6-Phosphate Dehydrogenase

Target: Glucose-6-Phosphate Dehydrogenase (G6PD)

Andere Bezeichnung: G6PD (G6PD Produkte)

Hintergrund: Glucose 6 Phosphate Dehydrogenase (G6PD) produces pentose sugars for nucleic acid synthesis and is the main producer of NADPH reducing power. Catalytic activity: D glucose 6 phosphate + NADP(+) = D glucono 1,5 lactone 6 phosphate + NADPH. Defects in G6PD are the cause of chronic non spherocytic haemolytic anemia (CNSHA). G6PD deficiency is the most common human enzyme deficiency, one benefit of having G6PD deficiency is that it confers a resistance to malaria.Synonyms: Glucose-6-P-Dehydrogenase, Glucose-6-phosphate 1-dehydrogenase

Gen-ID: 2539, 9606

UniProt: P11413

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones