TACR1 Antikörper (Internal Region)

Produktnummer ABIN374799

Dieses Anti-TACR1-Antikörper ist ein Ziege Polyklonal-Antikörper zur Detektion von TACR1 in WB. Geeignet für Human, Ratte, Maus und Hund.

Kurzübersicht für TACR1 Antikörper (Internal Region) (ABIN374799)

Target: TACR1 (Tachykinin Receptor 1 (TACR1))

Reaktivität: Human, Ratte, Maus, Hund

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser TACR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TACR1 Antikörper

Bindungsspezifität: Internal Region

Sequenz: C-EIPGDSSDRY HEQ

Spezifität: This antibody detects Tachykinin receptor 1 (TACR1).

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Rat, DogSpecies reactivity (tested):Human

Aufreinigung: Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Immunogen: Peptide from the internal region of the protein sequence according to NP_001049.1, NP_056542.1. Genename: TACR1

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: antibody detection limit dilution 1: 32000. Western blot: 1-3 μg/mL. Approx 36 kDa band observed in Human Testis lysates (calculatedMW of 35.6 kDa according to NP_056542.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.

Details zu TACR1

Target: TACR1 (Tachykinin Receptor 1 (TACR1))

Hintergrund: The neurokinin-1 (NK1) receptor is a G-protein-coupled receptor characterized by seven transmembrane helices which preferentially binds the neuropeptide substance P. NK1 receptor (also known as the Substance P Receptor) plays a key role in pain and inflammation. Studies also implicate NK1 receptor in depression and the growth of brain tumors. The NK1 receptor has been reported primarily in brain, and in blood lymphocytes, nose, small intestine, and stomach.Synonyms: NK-1 receptor, NK-1R, NK1R, SPR, Substance-P receptor, TAC1R

Gen-ID: 6869, 9606

UniProt: P25103

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour, Smooth Muscle Cell Migration