SDCBP Antikörper (N-Term)

Produktnummer ABIN374747

Der Ziege Polyklonal anti-SDCBP Antikörper wird verwendet zum Nachweis von SDCBP in Proben von Human, Ratte, Maus und Hund. Er wurde validiert für WB, IHC (p) und EIA.

Kurzübersicht für SDCBP Antikörper (N-Term) (ABIN374747)

Target: SDCBP (Syndecan Binding Protein (Syntenin) (SDCBP))

Reaktivität: Human, Ratte, Maus, Hund

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser SDCBP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-SDCBP Antikörper

Bindungsspezifität: N-Term

Spezifität: This antibody is expected to recognise isoform 1 (NP_005616.2 and NP_001007068.1) and isoform 3 (NP_001007070.1and NP_001007071.1) only.

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Rat, Canine.
Species reactivity (tested):Human.

Aufreinigung: Ammonium Sulphate precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

Immunogen: Peptide with sequence from the N-Terminus of Human Syntenin-1 / SDCBP (NP_005616.2, NP_001007068.1, NP_001007069, NP_001007070.1, NP_001007071.1). Genename: SLEDLKVDKVIQAQ-C

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: 1/128000. Western Blot: 0.01 - 0.03 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu SDCBP

Target: SDCBP (Syndecan Binding Protein (Syntenin) (SDCBP))

Andere Bezeichnung: Syntenin-1 / SDCBP

Hintergrund: Syntenin is an approximately 33 kDa scaffolding protein that that binds to kainate receptor subunits via a PDZ interaction. Syntenin has a tightly regulated developmental profile in neurons and is most abundant in the period of intense growth and synapse formation and stabilization (Hirbec et al, 2005). There is extensive colocalization of syntenin and kainate receptors with particularly intense labeling for both proteins at growth cones. It is proposed that syntenin has a role both in controlling membrane organization and in determining the formation and maturation of synapses.Synonyms: MDA-9, MDA9, Melanoma differentiation-associated protein 9, Pro-TGF-alpha cytoplasmic domain-interacting protein 18, SYCL, Scaffold protein Pbp1, Syndecan-binding protein 1, TACIP18

Gen-ID: 6386

NCBI Accession: NP_001007068

UniProt: O00560