LPIN3 Antikörper (Internal Region)

Produktnummer ABIN374744

Der Ziege Polyklonal anti-LPIN3 Antikörper wird verwendet zum Nachweis von LPIN3 in Proben von Human. Er wurde validiert für IHC (p).

Kurzübersicht für LPIN3 Antikörper (Internal Region) (ABIN374744)

Target: LPIN3 (Lipin 3 (LPIN3))

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser LPIN3 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-LPIN3 Antikörper

Bindungsspezifität: Internal Region

Spezifität: This antibody reacts to Lipin 3.

Aufreinigung: Affinity chromatography

Immunogen: Peptide with sequence C-KPKQKEDAVATD, from the internal region of the protein sequence

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: 1/64000. Western Blot: 0.1 μg/mL. Immunohistochemistry on paraffin sections: 2 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu LPIN3

Target: LPIN3 (Lipin 3 (LPIN3))

Andere Bezeichnung: Lipin-3

Hintergrund: Humans lipodystrophy is characterized by loss of body fat, fatty liver, hypertriglyceridemia, and insulin resistance. Mice carrying mutations in the fatty liver dystrophy (fld) gene have similar phenotypes. Through positional cloning, the mouse gene responsible for fatty liver dystrophy was isolated and designated Lpin1. The nuclear protein encoded by Lpin1 was named lipin. Lpin1 mRNA was expressed at high levels in adipose tissue and was induced during differentiation of preadipocytes. These results indicated that lipin is required for normal adipose tissue development and provided a candidate gene for human lipodystrophy. Through database searches, mouse and human EST and genomic sequences with similarities to Lpin1 were identified. These included two related mouse genes (Lpin2 and Lpin3) and three human homologs (LPIN1, LPIN2, and LPIN3).Synonyms: LIPN3L, LPIN3, Lipin-3-like, Lipin3

Gen-ID: 64900, 9606

UniProt: Q9BQK8