ALOX5 Antikörper (C-Term)

Produktnummer ABIN374732

Der Ziege Polyklonal anti-ALOX5 Antikörper wird verwendet zum Nachweis von ALOX5 in Proben von Human, Maus, Ratte und Hund. Er wurde validiert für WB.

Kurzübersicht für ALOX5 Antikörper (C-Term) (ABIN374732)

Target: ALOX5 (Arachidonate 5-Lipoxygenase (ALOX5))

Reaktivität: Human, Maus, Ratte, Hund

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser ALOX5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ALOX5 Antikörper

Bindungsspezifität: C-Term

Spezifität: This antibody reacts to Arachidonate 5-lipoxygenase.

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Canine.
Species reactivity (tested):Human, Rat.

Aufreinigung: Affinity chromatography

Immunogen: Peptide with sequence C-ERNKKKQLPYYYLSPD, from the C Terminus of the protein sequence Genename: ALOX5

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: 1/32000. Western Blot: 0.3 - 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu ALOX5

Target: ALOX5 (Arachidonate 5-Lipoxygenase (ALOX5))

Andere Bezeichnung: ALOX5 / LOG5

Hintergrund: The enzyme 5 Lipoxygenase (5 LO) plays a key role in regulating the production of leukotrienes (LTs). Overproduction of LTs contributes to several diseases, most notably chronic inflammatory diseases, including asthma, fibrosis and atherosclerosis. Recent work has demonstrated that the activity of 5 LO is regulated by PKA phosphorylation of serine 523 in 5 LO. Under normal conditions, this phosphorylation may be important in limiting inflammation. Abnormal signaling through cAMP and PKA, then, could contribute to a variety of diseases, including those characterized by chronic inflammation.Synonyms: 5-LO, 5-lipoxygenase, Arachidonate 5-lipoxygenase

Gen-ID: 240, 9606

UniProt: P09917