CHRM1 Antikörper (C-Term)

Produktnummer ABIN374726

Der Ziege Polyklonal anti-CHRM1 Antikörper wird verwendet zum Nachweis von CHRM1 in Proben von Ratte, Human, Maus und Hund. Er wurde validiert für WB.

Kurzübersicht für CHRM1 Antikörper (C-Term) (ABIN374726)

Target: CHRM1 (Muscarinic Acetylcholine Receptor M1 (CHRM1))

Reaktivität: Ratte, Human, Maus, Hund

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser CHRM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CHRM1 Antikörper

Bindungsspezifität: C-Term

Spezifität: This antibody reacts to M1 mAChR / CHRM1.

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Rat, Canine.
Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography

Immunogen: Peptide with sequence C-DKRRWRKIPKRPGSVH, from the C Terminus of the protein sequence

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: 1/16000. Western Blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu CHRM1

Target: CHRM1 (Muscarinic Acetylcholine Receptor M1 (CHRM1))

Andere Bezeichnung: Muscarinic Acetylcholine Receptor M1

Hintergrund: The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract. Muscarinic receptors are so called as they are more sensitive to the effects of the alkaloid muscarine, rather than nicotine.Synonyms: CHRM1, mAChR M1, mAChR-M1

Gen-ID: 1128

NCBI Accession: NP_000729

UniProt: P11229

Pathways: Synaptic Membrane