COMT Antikörper (Internal Region)

Produktnummer ABIN374718

Der Ziege Polyklonal anti-COMT Antikörper (ABIN374718) detektiert spezifisch COMT in WB und EIA. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für COMT Antikörper (Internal Region) (ABIN374718)

Target: COMT (Catechol-O-Methyltransferase (COMT))

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser COMT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-COMT Antikörper

Bindungsspezifität: Internal Region

Spezifität: This antibody is expected to recognizes both reported isoforms of COMT (NP_000745.1 and NP_009294.1).

Aufreinigung: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.

Immunogen: Peptide with sequence C-QDIIPQLKKKYDVD, from the internal region of the protein sequence (NP_000745.1 and NP_009294.1). Genename: COMT

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: Detection Limit Dilution: 1/64000. Western Blot: 0.03-0.1 μg/mL. Approx 28 kDa band and faint 28 kDa band observed inhuman testis lysates (calculated MW of 30.8 kDa according to NP_000745.1 and 24.8 kDaaccording to NP_009294.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu COMT

Target: COMT (Catechol-O-Methyltransferase (COMT))

Andere Bezeichnung: COMT

Hintergrund: Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease.Synonyms: Catechol O-methyltransferase

Gen-ID: 1312, 9606

UniProt: P21964

Pathways: Steroid Hormone Biosynthesis, SARS-CoV-2 Protein Interaktom