WT1 Antikörper (N-Term)

Produktnummer ABIN374714

Der Ziege Polyklonal Anti-WT1-Antikörper wurde für WB validiert. Er ist geeignet, WT1 in Proben von Human zu detektieren.

Kurzübersicht für WT1 Antikörper (N-Term) (ABIN374714)

Target: WT1 (Wilms Tumor 1 (WT1))

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser WT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-WT1 Antikörper

Bindungsspezifität: N-Term

Spezifität: This antibody reacts to Wilms tumor 1. This antibody is expected to recognise all four reported isoforms.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography

Immunogen: Peptide with sequence QDPASTCVPEPASQH, from the N Terminus of the protein sequence

Anwendungsinformationen

Applikationshinweise: ELISA: 1/4000. Western Blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3, 0.02 % sodium azide, 0.5 % bovine serum albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu WT1

Target: WT1 (Wilms Tumor 1 (WT1))

Andere Bezeichnung: WT1 / Wilms Tumor Protein

Hintergrund: WT1 encodes multiple isoforms of a zinc finger transcription factor essential for correct mammalian urogenital development. Different WT1 isoforms are thought to regulate transcription and participate in mRNA processing, functions reflected by a complex sub nuclear distribution. In humans, the preservation of the correct isoform ratio and their localization has been reported to be vital, and its disruption to result in disease. This gene has been reported as a useful marker for several types of illnesses. Mutations in this gene lead to the development of Wilm's Tumor, a sporadic and familial childhood kidney tumor.Synonyms: WT33

Gen-ID: 7490, 9606

UniProt: P19544

Pathways: Tube Formation