Moesin Antikörper (Internal Region)
Kurzübersicht für Moesin Antikörper (Internal Region) (ABIN374709)
Target
Alle Moesin (MSN) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Internal Region
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Sequenz
- C-NARDESKKTA ND
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Spezifität
- This antibody recognizes Moesin (Internal).
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Kreuzreaktivität (Details)
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Species reactivity (expected):Rat, Canine.
Species reactivity (tested):Human, Mouse. -
Aufreinigung
- Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
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Immunogen
- Peptide with sequence from the internal region of the protein sequence according to NP_002435.1. Genename: MSN
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Applikationshinweise
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ELISA: 1/16000. Western 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 0.5 mg/mL
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Buffer
- Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Moesin (MSN)
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Andere Bezeichnung
- Moesin
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Hintergrund
- Moesin is a member of the ERM (Ezrin-Radixin-Moesin) protein family, which possesses structural and probably functional relationships, they function as plasma membrane-actin cytoskeleton linkers and participate in the formation of specialized domains of the plasma membrane and are all localized to the submembranous cytoskeleton. Moesin is widely expressed in different tissues in cells, where it is localized to filopodia and other membranous protrusions that are important for cell-cell recognition and signalling and for cell movement. Moesin, a member of the talin-4.1 superfamily, is a linking protein of the submembraneous actin cytoskeleton. It is expressed in macrophages, lymphocytes, fibroblastic, endothelial, epithelial, and neuronal cell lines but not in blood cells. It is involved in cell adhesion, migration and organization of cell surface structures.Synonyms: MSN, Membrane-organizing extension spike protein
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Gen-ID
- 4478, 9606
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UniProt
- P26038
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Pathways
- Asymmetric Protein Localization
Target
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