Peroxiredoxin 2 Antikörper (C-Term)

Produktnummer ABIN374698

Dieser Ziege Polyklonal Antikörper detektiert spezifisch Peroxiredoxin 2 in WB und EIA. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für Peroxiredoxin 2 Antikörper (C-Term) (ABIN374698)

Target: Peroxiredoxin 2 (PRDX2)

Reaktivität: Human, Maus, Ratte

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser Peroxiredoxin 2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-Peroxiredoxin 2 Antikörper

Bindungsspezifität: C-Term

Sequenz: C-NVDDSKEYFS KHN

Spezifität: This antibody is expected to recognise isoforms a and b of Peroxiredoxin 2 only.

Kreuzreaktivität (Details): Species reactivity (expected):Rat.
Species reactivity (tested):Human, Mouse.

Aufreinigung: Affinity Chromatography

Immunogen: Peptide with sequence from the C Terminus of the protein sequence according to NP_005800.3, NP_859427.1.

Anwendungsinformationen

Applikationshinweise: ELISA: 1/16000. Western Blot: 0.3 - 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % Sodium Azide, pH ~7.3 with 0.5 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu Peroxiredoxin 2

Target: Peroxiredoxin 2 (PRDX2)

Andere Bezeichnung: Peroxiredoxin-2 / PRDX2

Hintergrund: The Peroxiredoxin (Prdx, Prx, or TrxPx) family of enzymes is a recently identified family of peroxidases found in free living organisms. The six known isoforms (Prx1 to 6) play an important role in protecting lipids, enzymes and DNA against peroxides, such as hydrogen peroxide. The ubiquitously expressed peroxiredoxins have also been shown to play a role in apoptosis and cell differentiation. This is acomplished by the active cysteine of Prx reducing peroxides, which is then converted into a transient cysteine sulfenic acid or cysteine sulfinic acid. If Prx protection is inadequate against peroxidases, the resulting protein and DNA damage may result in neurological disease such as Alzheimer's or DNA damage leading to cancer.Synonyms: NKEF-B, NKEFB, Natural killer cell-enhancing factor B, PRDX-2, PRP, Prx-2, Prx2, TDPX1, TSA, Thiol-specific antioxidant protein, Thioredoxin peroxidase 1, Thioredoxin-dependent peroxide reductase 1

Gen-ID: 7001, 9606

UniProt: P32119