Adenosine A2b Receptor Antikörper (C-Term)

Produktnummer ABIN374607

Der Ziege Polyklonal anti-Adenosine A2b Receptor Antikörper (ABIN374607) detektiert spezifisch Adenosine A2b Receptor in IHC (p) und EIA. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Adenosine A2b Receptor Antikörper (C-Term) (ABIN374607)

Target: Adenosine A2b Receptor (ADORA2B)

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser Adenosine A2b Receptor Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-Adenosine A2b Receptor Antikörper

Bindungsspezifität: C-Term

Sequenz: CQADVKSGNG Q

Spezifität: This anitbody recognizes Adenosine receptor A2b.

Aufreinigung: Affinity chromatography

Immunogen: Peptide with sequence from the C Terminus of the protein sequence (NP_000667.1). Genename: ADORA2B

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: 1/4000. Western Blot. Immunohistochemistry on paraffin sections: 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu Adenosine A2b Receptor

Target: Adenosine A2b Receptor (ADORA2B)

Andere Bezeichnung: Adenosine Receptor A2b

Hintergrund: Adenosine is involved in a variety of processes, including the synthesis of urea, the anti-inflammatory response, and the inhibition of protein synthesis. The adenosine receptors, including adenosine A1-R, adenosine A2A-R, adenosine A2B-R, and adenosine A3-R, are integral membrane proteins that are members of the G protein-coupled receptor family. The A1-R protein mediates ureagenesis in a partially calcium-dependent manner. Adenosine is known to mediate coronary vasodilation via the A2A-R receptor. Collagen synthasis and total protein synthesis are inhibited in certain cells by adenosine, acting via the A2B receptors. Activation of the A3-R receptor inhibits the induction of the cytokine TNFα and blocks the endotoxin CD14 receptor signal transduction pathway.Synonyms: ADORA2B

Gen-ID: 136, 9606

UniProt: P29275

Pathways: cAMP Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process