DDC Antikörper (C-Term)

Produktnummer ABIN374555

Produktdetails anti-DDC Antikörper

Target: DDC (Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase) (DDC))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser DDC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: This antibody reacts to DOPA decarboxylase.

Aufreinigung: Affinity chromatography

Immunogen: Peptide with sequence C-WEHIKELAADVL, from the C Terminus of the protein sequence

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: 1/8000. Western Blot: 0.03 - 0.1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu DDC

Target: DDC (Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase) (DDC))

Andere Bezeichnung: AADC / DDC (DDC Produkte)

Synonyme: AADC antikoerper, wu:fa56d05 antikoerper, wu:fd59h03 antikoerper, wu:fk20h01 antikoerper, zgc:65801 antikoerper, zgc:76929 antikoerper, Ddc antikoerper, DdcDv antikoerper, Dvir\\GJ17995 antikoerper, GJ17995 antikoerper, dvir_GLEANR_2561 antikoerper, Aadc antikoerper, 5-HT antikoerper, CG10697 antikoerper, DDC antikoerper, DdcDm antikoerper, Dmel\\CG10697 antikoerper, ddc antikoerper, fDDC antikoerper, l(2)37Bl antikoerper, l(2)37Ch antikoerper, l(2)k02104 antikoerper, dopa decarboxylase antikoerper, Dopa-decarboxylase antikoerper, dopa decarboxylase (aromatic L-amino acid decarboxylase) antikoerper, Dopa decarboxylase antikoerper, dopa decarboxylase L homeolog antikoerper, DDC antikoerper, ddc antikoerper, Ddc antikoerper, Dvir\Ddc antikoerper, ddc.L antikoerper

Hintergrund: DOPA decarboxylase is an enzyme implicated in 2 metabolic pathways, synthesizing 2 important neurotransmitters: dopamine and serotonin which both play key roles in many clinical disorders, including Parkinson's disease. Following the hydroxylation of tyrosine to form L dihydroxyphenylalanine (LDOPA), catalyzed by tyrosine hydroxylase, DDC decarboxylates LDOPA to form dopamine. This neurotransmitter is found in different areas of the brain and is particularly abundant in basal ganglia. Dopamine is also produced by DDC in the sympathetic nervous system and is the precursor of the catecholaminergic hormones, noradrenaline and adrenaline in the adrenal medulla. In the nervous system, tryptophan hydroxylase produces 5 OH tryptophan, which is decarboxylated by DDC, giving rise to serotonin. DDC is a homodimeric, pyridoxal phosphate dependent enzyme.Synonyms: Aromatic-L-amino-acid decarboxylase, DOPA decarboxylase

Gen-ID: 1644, 9606

UniProt: P20711

Pathways: Dopaminergic Neurogenesis