FTCD Antikörper (Internal Region)

Produktnummer ABIN374454

Der Ziege Polyklonal anti-FTCD Antikörper (ABIN374454) detektiert spezifisch FTCD in WB, IHC (p) und EIA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte und Schwein.

Kurzübersicht für FTCD Antikörper (Internal Region) (ABIN374454)

Target: FTCD (Formiminotransferase Cyclodeaminase (FTCD))

Reaktivität: Human, Maus, Ratte, Schwein

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser FTCD Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-FTCD Antikörper

Bindungsspezifität: Internal Region

Sequenz: CLREQGRGKD QPGRL

Spezifität: This antibody recognizes 58KGolgi protein (Internal).

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Rat and Pig.
Species reactivity (tested):Human.

Aufreinigung: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

Immunogen: Peptide from the internal region of the protein sequence according to NP_006648.1, NP_996848.1 Genename: FTCD

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: Antibody Detection Limit: 1/64000. Western blot: 0.01-0.03 μg/mL. Detects a approx. 60 kDa band in Human Liver lysates (calculatedMW of 58.0 kDa according to NP_006648.1 and NP_996848.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu FTCD

Target: FTCD (Formiminotransferase Cyclodeaminase (FTCD))

Andere Bezeichnung: 58K Golgi Protein

Hintergrund: 58K Golgi protein antibodies are excellent for use as markers for the Golgi complex. The 58K Golgi protein has been identified as being FTCD, a bifunctional enzyme that channels 1-carbon units from formiminoglutamate, a metabolite of the histidine degradation pathway, to the folate pool. Defects in FTCD are the cause of glutamate formiminotransferase deficiency, also known as formiminoglutamicaciduria (FIGLU-uria). It is an autosomal recessive disorder. Features of a severe phenotype, include elevated levels of formiminoglutamate (FIGLU) in the urine in response to histidine administration, megaloblastic anemia, and mental retardation. Features of a mild phenotype include high urinary excretion of FIGLU in the absence of histidine administration, mild developmental delay, and no hematological abnormalities.Synonyms: FTCD, Formimidoyltransferase-cyclodeaminase, Formiminotransferase-cyclodeaminase, Golgi Marker 58K, Golgi marker, LCHC1

Gen-ID: 10841, 9606

UniProt: O95954