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PITPNM1 Antikörper (C-Term)

PITPNM1 Reaktivität: Human, Maus, Rind (Kuh), Hund WB, IF Wirt: Ziege Polyclonal unconjugated
Produktnummer ABIN374422
  • Target Alle PITPNM1 Antikörper anzeigen
    PITPNM1 (Phosphatidylinositol Transfer Protein, Membrane-Associated 1 (PITPNM1))
    Bindungsspezifität
    • 15
    • 9
    • 6
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 36
    • 19
    • 9
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Rind (Kuh), Hund
    Wirt
    • 49
    • 1
    • 1
    Ziege
    Klonalität
    • 50
    Polyklonal
    Konjugat
    • 17
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PITPNM1 Antikörper ist unkonjugiert
    Applikation
    • 24
    • 23
    • 13
    • 13
    • 7
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Sequenz
    C-KARSISLKLD SEE
    Spezifität
    This antibody detects NIR2 at C-term and is expected to recognise both reported isoforms.
    Kreuzreaktivität (Details)
    Species reactivity (expected):Human, Dog, Cow.
    Species reactivity (tested):Mouse.
    Aufreinigung
    Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
    Immunogen
    Peptide from the C-Terminus of the protein sequence according to NP_004901.2, NP_001124320.1. Genename: PITPNM1
    Top Product
    Discover our top product PITPNM1 Primärantikörper
  • Applikationshinweise
    Peptide ELISA: Limit dilution 1: 8000. Western blot: Customer's experiments gave a band at approx 160 kDa in lysates of a MouseMacrophage cell line after 2 μg/mL antibody staining (calculated MW of 130 kDa accordingto NP_004901.1). In ICC the customer found staining of vesicular cytoplasm in the samecell line.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.5 mg/mL
    Buffer
    Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    PITPNM1 (Phosphatidylinositol Transfer Protein, Membrane-Associated 1 (PITPNM1))
    Andere Bezeichnung
    NIR2 (PITPNM1 Produkte)
    Synonyme
    DRES9 antikoerper, Mpt-1 antikoerper, Nir-2 antikoerper, PITPnm 1 antikoerper, Pitpnm antikoerper, R75447 antikoerper, Rd9 antikoerper, RdgB antikoerper, RdgB1 antikoerper, NIR2 antikoerper, PITPNM antikoerper, RDGB antikoerper, RDGB1 antikoerper, RDGBA antikoerper, RDGBA1 antikoerper, phosphatidylinositol transfer protein membrane associated 1 antikoerper, phosphatidylinositol transfer protein, membrane-associated 1 antikoerper, PITPNM1 antikoerper, Pitpnm1 antikoerper
    Hintergrund
    NIR2 belongs to a family of proteins that share homology with the Drosophila retinal degeneration B (rdgB) protein. Nir2, a human homolog of Drosophila melanogaster retinal degeneration B protein, is essential for cytokinesis. A specific Thr residue in the Nir2 PI-transfer domain provides a regulatory site for targeting to lipid droplets. This may affect intracellular lipid trafficking and distribution & explain the dominant effect of the RdgB-T59E mutant on retinal degeneration.Synonyms: DRES9, Membrane-associated phosphatidylinositol transfer protein 1, NIR2, PITPNM, PITPNM1
    Gen-ID
    9600
    NCBI Accession
    NP_004901
    UniProt
    O00562
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