MORF4L2 Antikörper (N-Term)

Produktnummer ABIN374201

Der Ziege Polyklonal Anti-MORF4L2-Antikörper wurde für WB validiert. Er ist geeignet, MORF4L2 in Proben von Human und Hund zu detektieren.

Kurzübersicht für MORF4L2 Antikörper (N-Term) (ABIN374201)

Target: MORF4L2 (Mortality Factor 4 Like 2 (MORF4L2))

Reaktivität: Human, Hund

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser MORF4L2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MORF4L2 Antikörper

Bindungsspezifität: N-Term

Spezifität: This antibody detects MORF4L2 at N-term.

Kreuzreaktivität (Details): Species reactivity (expected):Canine.
Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography

Immunogen: Peptide with sequence SSRKQGSQPRGQQS-C, from the N Terminus of the protein sequence Genename: MORF4L2

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: 1/32000. Western blot: 1 - 3 μg/mL. Approx 35 kDa band observed in Human Brain and A431 lysates(calculated MW of 32.5 kDa according to NP_036418.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu MORF4L2

Target: MORF4L2 (Mortality Factor 4 Like 2 (MORF4L2))

Andere Bezeichnung: MORF4L2

Hintergrund: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes mainly by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also be involved in DNA repair when directly recruited to sites of DNA damage. Also component of the MSIN3A complex which acts to repress transcription by deacetylation of nucleosomal histones. May also interact with one or more as yet undefined members of the TLE (transducin like enhancer of split) family of transcriptional repressors.Synonyms: KIAA0026, MORF-related gene X protein, MORF4L2, MRGX, MSL3-2 protein, Mortality factor 4-like protein 2, Transcription factor-like protein MRGX

Gen-ID: 9643

NCBI Accession: NP_036418

UniProt: Q15014

Pathways: Regulation of Muscle Cell Differentiation