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BCAP31 Antikörper (C-Term)

Dieses Ziege Polyklonal-Antikörper erkennt spezifisch BCAP31 in WB. Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN374194

Kurzübersicht für BCAP31 Antikörper (C-Term) (ABIN374194)

Target

Alle BCAP31 Antikörper anzeigen
BCAP31 (B-Cell Receptor-Associated Protein 31 (BCAP31))

Reaktivität

  • 57
  • 24
  • 13
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 50
  • 7
  • 1
Ziege

Klonalität

  • 40
  • 18
Polyklonal

Konjugat

  • 35
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
Dieser BCAP31 Antikörper ist unkonjugiert

Applikation

  • 41
  • 23
  • 17
  • 17
  • 11
  • 8
  • 7
  • 5
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 6
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    Sequenz

    C-QAAVDGPMDK KEE

    Spezifität

    This antibody detects BCAP31 / BAP31 at C-term.

    Aufreinigung

    Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

    Immunogen

    Peptide from C Terminus of the protein sequence according to NP_001132929.1, NP_005736.3, NP_001132913.1. Genename: BCAP31
  • Applikationshinweise

    Peptide ELISA: Limit dilution 1: 4000. Western blot: 1-3 μg/mL. Approx 30 kDa band observed in Human Placenta and Brain lysate(predicted MW of 20 kDa according to NP_005736).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    0.5 mg/mL

    Buffer

    Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C/-20 °C

    Informationen zur Lagerung

    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.
  • Target

    BCAP31 (B-Cell Receptor-Associated Protein 31 (BCAP31))

    Andere Bezeichnung

    BCAP31 / BAP31

    Hintergrund

    BAP31 (B Cell Receptor Associated Protein, 28 kDa) is a multiple membrane spanning protein of the endoplasmic reticulum. It has been shown to form both homo and hetero oligomers with the closely related BAP29, and is a potential apoptotic regulator as a predicted BCL2/BCLXL associated protein. In the C terminal domain of BAP31, there are two identical recognition sites for initiator Caspases 1 and 8 of the programmed death cascade. It is hypothesized that BAP31 plays a role in the transport of selected proteins to the Golgi apparatus. BAP31 has also been shown to control expression of CFTR (cystic fibrosis transmembrane conductance regulator). It is believed that interference with the expression or function of BAP31 in epithelial cells may be a way to circumvent the chloride channel defect in cystic fibrosis.Synonyms: 6C6-AG tumor-associated antigen, B-cell receptor-associated protein 31, BCR-associated protein Bap31, DXS1357E, Protein CDM, p28 Bap31

    Gen-ID

    10134

    NCBI Accession

    NP_001132929

    UniProt

    P51572

    Pathways

    Positive Regulation of Endopeptidase Activity
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