CREB3L4 Antikörper (C-Term)

Produktnummer ABIN374193

Der Ziege Polyklonal anti-CREB3L4 Antikörper (ABIN374193) detektiert spezifisch CREB3L4 in WB und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für CREB3L4 Antikörper (C-Term) (ABIN374193)

Target: CREB3L4 (cAMP Responsive Element Binding Protein 3-Like 4 (CREB3L4))

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser CREB3L4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-CREB3L4 Antikörper

Bindungsspezifität: C-Term

Sequenz: C-PSGRIRSVLH ADEM

Spezifität: This antibody detects CREB3L4 / AIBZIP at C-term.

Aufreinigung: Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Immunogen: Peptide from C Terminus of the protein sequence according to NP_570968.1 Genename: CREB3L4

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: Limit dilution 1: 32000. Western blot: 0.5-2 μg/mL. Approx 50 kDa band observed in Human Placenta lysate(predicted MW of 40 kDa according to NP_570968). Immunohistochemistry: 2-4 μg/mL. In paraffin embedded Human Prostate shows strongstaining of cytoplasm in the secretory cells of the gland.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.

Details zu CREB3L4

Target: CREB3L4 (cAMP Responsive Element Binding Protein 3-Like 4 (CREB3L4))

Andere Bezeichnung: CREB3L4 / AIBZIP

Hintergrund: Androgen-induced basic leucine zipper (AIBZIP)is a transcription factor. AIbZIP is a 395 aa protein with homology to cyclic AMP-responsive element binding protein/activating transcription factor. It contains an NH(2)-terminal activation domain, a central bZIP domain, and a COOH-terminal transmembrane domain. Immunoreactive AIbZIP protein has been detected in the cytoplasm of prostatic luminal epithelial cells, full-length AIbZIP-GFP fusion proteins are localized in the cytoplasm of LNCaP cells, while a truncated form of AIbZIP lacking the putative transmembrane domain was exclusively nuclear. AIbZIP is expressed at higher levels in cancerous prostate cells compared with noncancerous prostate cells.Synonyms: Androgen-induced basic leucine zipper protein, Attaching to CRE-like 1, CREB4, Cyclic AMP-responsive element-binding protein 3-like protein 4, JAL, Transcript induced in spermiogenesis protein 40, cAMP-responsive element-binding protein 3-like protein 4, hJAL

Gen-ID: 148327

NCBI Accession: NP_570968

UniProt: Q8TEY5

Pathways: Thyroid Hormone Synthesis