BAIAP2 Antikörper (C-Term, Isoform 3)

Produktnummer ABIN374111

Der Ziege Polyklonal anti-BAIAP2 Antikörper wird verwendet zum Nachweis von BAIAP2 in Proben von Human, Hund und Rind (Kuh). Er wurde validiert für WB.

Kurzübersicht für BAIAP2 Antikörper (C-Term, Isoform 3) (ABIN374111)

Target: BAIAP2 (BAI1-Associated Protein 2 (BAIAP2))

Reaktivität: Human, Hund, Rind (Kuh)

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser BAIAP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-BAIAP2 Antikörper

Bindungsspezifität: C-Term, Isoform 3

Sequenz: C-SMSSADVEVA RF

Spezifität: This antibody will recognise only one of three reported isoforms (NP_006331.1) (Isofom 3).

Kreuzreaktivität (Details): Species reactivity (expected):Canine (Dog), Bovine.
Species reactivity (tested):Human.

Aufreinigung: Ammonium Sulphate precipitation followed by antigen Affinity Chromatography using the immunizing peptide

Immunogen: Peptide from the C-Terminus of the protein sequence according to NP_006331.1. Genename: BAIAP2

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: Limit dilution 1: 16000. Western blot: 1-3 μg/mL. Approx 55 kDa band observed in Human Brain (Cerebellum andFrontal Cortex) lysates (calculated MW of 57.5 kDa according to NP_006331.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C.

Details zu BAIAP2

Target: BAIAP2 (BAI1-Associated Protein 2 (BAIAP2))

Andere Bezeichnung: BAIAP2

Hintergrund: BAIAP2, a target of p53, has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This interaction at the cytoplasmic membrane is crucial to the function of this protein, which may be involved in neuronal growth-cone guidance. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis.Synonyms: BAI-associated protein 2, BAI1-associated protein 2, BAP2, Brain-specific angiogenesis inhibitor 1-associated protein 2, FLAF3, Fas ligand-associated factor 3, IRS-58, IRSp53, IRSp53/58, Insulin receptor substrate p53, Insulin receptor substrate p53/p58, Insulin receptor substrate protein of 53 kDa

Gen-ID: 10458

NCBI Accession: NP_006331

UniProt: Q9UQB8