BAG2 Antikörper (C-Term)

Produktnummer ABIN374110

Dieses Ziege Polyklonal-Antikörper erkennt spezifisch BAG2 in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für BAG2 Antikörper (C-Term) (ABIN374110)

Target: BAG2 (BCL2-Associated Athanogene 2 (BAG2))

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser BAG2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-BAG2 Antikörper

Bindungsspezifität: C-Term

Sequenz: CSKTLQQNAE SRFN

Spezifität: This antibody detects BAG2 at C-term.

Aufreinigung: Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Immunogen: Peptide from C Terminus of the protein sequence according to NP_004273.1. Genename: BAG2

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: Limit dilution 1: 8000. Western blot: 0.1-0.3 μg/mL. Approx 25 kDa band observed in Human HeLa lysates(calculated MW of 23.5 kDa according to NP_004273.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.

Details zu BAG2

Target: BAG2 (BCL2-Associated Athanogene 2 (BAG2))

Andere Bezeichnung: BAG2

Hintergrund: BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.Synonyms: BAG family molecular chaperone regulator 2, BAG-2, Bcl-2-associated athanogene 2

Gen-ID: 9532

NCBI Accession: NP_004273

UniProt: O95816