GRAP2 Antikörper (C-Term)

Produktnummer ABIN374093

Der Ziege Polyklonal anti-GRAP2 Antikörper wird verwendet zum Nachweis von GRAP2 in Proben von Human, Maus und Schwein. Er wurde validiert für WB.

Kurzübersicht für GRAP2 Antikörper (C-Term) (ABIN374093)

Target: GRAP2 (GRB2-Related Adaptor Protein 2 (GRAP2))

Reaktivität: Human, Maus, Schwein

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser GRAP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GRAP2 Antikörper

Bindungsspezifität: C-Term

Spezifität: This antibody detects GRAP2 at C-term.

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Porcine.
Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography

Immunogen: Peptide with sequence C-GLFPANYVAPMTR, from the C Terminus of the protein sequence Genename: GRAP2

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: 1/32000. Western blot: 1 - 3 μg/mL. Approx 38 kDa band seen in Jurkat lysate.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu GRAP2

Target: GRAP2 (GRB2-Related Adaptor Protein 2 (GRAP2))

Andere Bezeichnung: GRAP2

Hintergrund: GRAP2 is a member of the GRB2/Sem5/Drk family. This member is an adaptor-like protein involved in leukocyte-specific protein-tyrosine kinase signaling. Like its related family member, GRB2-related adaptor protein (GRAP), this protein contains an SH2 domain flanked by two SH3 domains. This protein interacts with other proteins, such as GRB2-associated binding protein 1 (GAB1) and the SLP-76 leukocyte protein (LCP2), through its SH3 domains. Transcript variants utilizing alternative polyA sites exist.Synonyms: Adapter protein GRID, GADS, GRB-2-like protein, GRB2-related adapter protein 2, GRB2L, GRBLG, GRBX, GRID, Grf-40, Grf40 adapter protein, Growth factor receptor-binding protein, Hematopoietic cell-associated adapter protein GrpL, SH3-SH2-SH3 adapter Mona

Gen-ID: 9402

NCBI Accession: NP_004801

UniProt: O75791

Pathways: T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung