Reticulon 4 Antikörper (N-Term)

Produktnummer ABIN372912

Dieses Anti-Reticulon 4-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Reticulon 4 in WB, IHC (p) und EIA. Geeignet für Human, Maus und Ratte.

Kurzübersicht für Reticulon 4 Antikörper (N-Term) (ABIN372912)

Target: Reticulon 4 (RTN4)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Reticulon 4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-Reticulon 4 Antikörper

Bindungsspezifität: N-Term

Spezifität: This antibody reacts to Neuroendocrine-specific Protein C (RTN4/NOGO).

Kreuzreaktivität (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: Immunoaffinity Chromatography.

Immunogen: Synthetic peptide - KLH conjugated corresponding to 23 amino acids from near the amino terminus of Human NOGO-A.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western blot: 0.5-1.0 μg/mL. Immunohistochemistry on Paraffin Sections: 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu Reticulon 4

Target: Reticulon 4 (RTN4)

Andere Bezeichnung: Reticulon-4 / RTN4

Hintergrund: Adult mammalian axon regeneration is generally successful in the peripheral nervous system but poor in the central nervous system. Inhibition results from physical barriers imposed by glial scars, a lack of neurotrophic factors, and growth inhibitory molecules associated with myelin, the insulating axon sheath. These molecules include NI35, myelin associated glycoprotein, and Nogo (Neurite Outgrowth Inhibitor). Nogo is a potent neurite outgrowth inhibitor which may also help block the regeneration of the central nervous system in adults.Synonyms: Foocen, KIAA0886, NOGO, NSP, Neurite outgrowth inhibitor, Neuroendocrine-specific protein, Neuroendocrine-specific protein C homolog, Reticulon-5

Gen-ID: 57142

NCBI Accession: NP_008939

UniProt: Q9NQC3

Pathways: Neurotrophin Signalübertragung, Regulation of Cell Size, SARS-CoV-2 Protein Interaktom